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Microdosing with psychedelics, the practice of taking a low dose of a psychedelic every couple of days, seems to be an increasing trend among science, technology, engineering, and mathematics professionals. Multiple anecdotal reports suggest performance enhancing effects; however, these positive reports may overshadow potential negative experiences. The present study aimed to assess motives to microdose and potential negative effects. Findings show that the majority of the respondents indeed microdose to enhance performance. Only one-fifth experienced negative effects of which most occurred acutely after consumption of the substance. Negative effects were not a reason to stop microdosing whereas absence of self-rated efficacy was.

The present study aimed to investigate in http://www.dosetherapy.org/, by means of an online questionnaire, the history of psychedelic use among microdosers, the dose and schedule they use, the prevalence of microdosing in the work environment, their motivation to microdose, and the potential negative effects. The survey was not specifically advertised as a microdosing survey but rather a psychedelic survey in general. Detailed questions about motives to use were only presented for microdosing since the study was not set up to test differences in motivations for use of regular doses and microdoses.

Psilocybin and psilocin are absorbed by the mucous membranes of the mouth and the stomach. The effects are noticeable within 15 to 60 minutes and last between 2 and 8 hours. The duration depends on the type of truffles or magic mushrooms you are taking, the quantity you have taken and your metabolism. The chemical makeup of your brain also has an influence on the effects check it out at http://www.dosetherapy.org/.

The usual dose is between 10 and 30 milligrams, but some people have a heightened sensitivity to psilocybin and psilocin, causing them to already notice effects after ingesting 2 milligrams. Therefore, when taking truffles or magic mushrooms for the first time, it is important to not take too much and to find out how your body responds to truffles and magic mushrooms. Your mind and body quickly get used to the use of psilocybin and psilocin, but that habituation also disappears quickly. If you take magic mushrooms or truffles three or four times a week, the effects may diminish, but that habituation will also disappear within a few days. If you take truffles or magic mushrooms often, you will sometimes have to take a break for 5 to 7 days to avoid diminishing effects.